I've never been Doug Stanhope's biggest fan but he's right on this (except perhaps the trip to Reno):
There is no such thing as laughing at something you shouldn’t. You should laugh everywhere you can find even the slightest glimmer of humour. Life is a series of heartache, tragedy and injustice, punctuated by a few cocktails and that one trip to Reno. The more you can laugh at the ugliest parts, the better off you are.
Go and read the rest (and try not to be offended, OK?)
h/t that annoying moggie